Mutation Information
Mutation Site
|
M204I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Literature Information
PubMed PMID
|
16220028
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2005 |
Journal
|
Le infezioni in medicina |
Title
|
Hepatitis B virus DNA quantitation and detection of core promoter, precore and polymerase mutations in chronic hepatitis B: evaluation and clinical usefulness of three new commercial assays. |
Author
|
Zampino R,Marrone A,Finnström N,Eriksson T,Törmänen V,Hedrum A,Attanasio V,Rosario P,Utili R,Ruggiero G |
Evidence
|
Affigene HBV mutant VL (positions G1764A, G1896A) and affigene HBV DE/3TC (positions rtL180M, rtM204V/I) were able to detect a low presence of mutants in a mixed population (wild type and mutant) compared to direct sequencing and Inno-LIPA HBV DR, which identified only the dominant population.
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