HBV Mutation Detail Information

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Mutation Information

Mutation Site	L115Y
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	D
Country	Iran

Literature Information

PubMed PMID	21671883
Disease	HBV-HIV coinfection
Published Year	2011
Journal	Current HIV research
Title	Detection of hepatitis B virus variants in HBV monoinfected and HBV/HIV coinfected Iranian patients under lamivudine treatment.
Author	Aghasadeghi MR,Bahramali G,Sadat SM,Farahani A,Mohraz M,Davar Siadat S,Mostafavi E,Memarnejadian A,Ardestani MS,Vahabpour R,Saraji AA,Delbaz SA
Evidence	A significant association between subtypes and mutations of rtS135Y (12.5% ayw2, 81.2% ayw3, 6.3% ayw4, P<0.0001), rtL115Y (85.7% ayw3, 14.28% ayw4, P=0.003),rtM204I (100% ayw2, P=0.03), sD144E (63% ayw2, 87.5%ayw3, 6.3% ayw4, P<0.001) and sS136Y (6.3% ayw2,87.5% ayw3, 6.3% ayw4, P<0.001) was also observed.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation