Mutation Information
Mutation Site
|
L336M |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Country
|
China |
Literature Information
PubMed PMID
|
28325923
|
Disease
|
HBV infection
|
Published Year
|
2017 |
Journal
|
Emerging microbes & infections |
Title
|
Clinical features and viral quasispecies characteristics associated with infection by the hepatitis B virus G145R immune escape mutant. |
Author
|
Xue Y,Wang MJ,Yang ZT,Yu DM,Han Y,Huang D,Zhang DH,Zhang XX |
Evidence
|
The frequencies of four mutations in the S region (G145R, K160R, L173P and Q181R), four mutations in the RT region (R153Q, S256G, C332S and L336M) and five mutations in the X region (S54P, L55F, R56P, L58P and C69P) decreased in the 8th week, whereas the frequencies of many mutations in the S, P and X regions clearly increased.
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