|
Mutation Information
|
Mutation Site
|
Q215S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
19550344
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2010 |
|
Journal
|
European journal of gastroenterology & hepatology |
|
Title
|
Monitoring of therapy in patients with chronic hepatitis B virus. |
|
Author
|
Arrese E,Basaras M,Blanco S,Ruiz P,Cisterna R |
|
Evidence
|
With regard to this case, the same results were observed by INNO-LiPA HBV DR v3 and direct sequencing, but by direct sequencing we detected an extra mutation rtQ215S that was present in two patients: one patient who was on treatment with LAM had an rtQ215S mutation in addition to an rtM204I, and the second patient treated with ADV had rtA181V.
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HBV Mutation Detail Information