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Mutation Information
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Mutation Site
|
Q215H |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM);adefovir (ADV) |
|
Country
|
China |
Literature Information
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PubMed PMID
|
30906435
|
|
Disease
|
Chronic hepatitis B
|
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Published Year
|
2019 |
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Journal
|
Experimental and therapeutic medicine |
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Title
|
Viral quasispecies of hepatitis B virus in patients with YMDD mutation and lamivudine resistance may not predict the efficacy of lamivudine/adefovir rescue therapy. |
|
Author
|
Wang C,Yu S,Zhang Y,Zhang M,Lv L,Huang C,Li X,Li J,Zhang Z |
|
Evidence
|
Common and frequent mutations identified in the cohort of the present study included rtL80V/I, rtV84M, rtL91I, rtN118H/D/T, rtT128A, rtL180M, rtT184L/S/A, rtV191I, rtS202G, rtV207I/M, rtS213T, rtQ215P/S/H, rtL229V/M/W/F, rtS256G/C, and rtN337H/T, as presented in Table II. I
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HBV Mutation Detail Information