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Mutation Information
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Mutation Site
|
T184A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.T184A+rt.M204I+rt.M204V+rt.L180M |
|
Relevant Drug
|
entecavir (ETV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
29119303
|
|
Disease
|
HBV infection
|
|
Published Year
|
2018 |
|
Journal
|
Virus genes |
|
Title
|
Evolution of drug-resistant mutations in HBV genomes in patients with treatment failure during the past seven years (2010-2016). |
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Author
|
Zhang HY,Liu LG,Ye CY,Chen CH,Hang SX,Zhu Z,Shen HY,Huang ZY,Chen WY,Xue Y |
|
Evidence
|
For ETV, rtL180M + M204V/I + S202G and rtL180M + M204V/I + T184A, which accounted for 73.33%, were the most common patterns. For MDR mutations, patterns contained rtA181T/V accounted for 98.34%.
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HBV Mutation Detail Information