Mutation Information
Mutation Site
|
M204I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Literature Information
PubMed PMID
|
20937597
|
Disease
|
HBV infection
|
Published Year
|
2010 |
Journal
|
Bioinformatics (Oxford, England) |
Title
|
A classification model for G-to-A hypermutation in hepatitis B virus ultra-deep pyrosequencing reads. |
Author
|
Reuman EC,Margeridon-Thermet S,Caudill HB,Liu T,Borroto-Esoda K,Svarovskaia ES,Holmes SP,Shafer RW |
Evidence
|
For example, two of the most common hepatitis B virus (HBV) reverse transcriptase (RT) drug-resistance mutations, A181T and M204I, arise from G --> A changes and are routinely detected as low-abundance variants in nearly all HBV deep sequencing samples.
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