|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
E |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Angola |
Literature Information
|
PubMed PMID
|
24632784
|
|
Disease
|
HBV infection
|
|
Published Year
|
2014 |
|
Journal
|
PloS one |
|
Title
|
Analysis of complete nucleotide sequences of Angolan hepatitis B virus isolates reveals the existence of a separate lineage within genotype E. |
|
Author
|
Lago BV,Mello FC,Ribas FS,Valente F,Soares CC,Niel C,Gomes SA |
|
Evidence
|
The two others, LDA173 and LDA339, displayed the lamivudine resistance triple mutation rtV173L, rtL180M, rtM204V/I which causes the concomitant amino acid substitutions E164D/G and I195M in the small S protein (Table 3)..
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HBV Mutation Detail Information