|
Mutation Information
|
Mutation Site
|
L181W |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV);lamivudine (LAM) |
|
Country
|
Turkey |
Literature Information
|
PubMed PMID
|
24175847
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2013 |
|
Journal
|
Asian Pacific journal of cancer prevention : APJCP |
|
Title
|
Prevelance of common YMDD motif mutations in long term treated chronic HBV infections in a Turkish population. |
|
Author
|
Alagozlu H,Ozdemir O,Koksal B,Yilmaz A,Coskun M |
|
Evidence
|
Three of the mutated samples (7.5%) having codon rtL181W due to the missense transversion point mutations and showed resistance to combined adefovir and lamivudin.
|
|
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HBV Mutation Detail Information