HBV Mutation Detail Information

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Mutation Information

Mutation Site	L217P
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Country	China

Literature Information

PubMed PMID	21056552
Disease	Chronic hepatitis B
Published Year	2011
Journal	Clinica chimica acta; international journal of clinical chemistry
Title	Variable influence of mutational patterns in reverse-transcriptase domain on replication capacity of hepatitis B virus isolates from antiviral-experienced patients.
Author	Ji D,Liu Y,Si LL,Li L,Chen GF,Xin SJ,Zhao JM,Xu D
Evidence	Compared to wild-type counterpart, mutant rtL217P produced 1.98-fold higher replicative intermediate level, and mutant rtM204I+rtL217P increased the replicative intermediate level to 1.20 fold.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation