HBV Mutation Detail Information

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Mutation Information
Mutation Site A194T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype A
Relevant Drug tenofovir (TDF);lamivudine (LAM);entecavir (ETV);telbivudine (LDT)
Literature Information
PubMed PMID 19263474
Published Year 2009
Journal Hepatology (Baltimore, Md.)
Title The rtA194T polymerase mutation impacts viral replication and susceptibility to tenofovir in hepatitis B e antigen-positive and hepatitis B e antigen-negative hepatitis B virus strains.
Author Amini-Bavil-Olyaee S,Herbers U,Sheldon J,Luedde T,Trautwein C,Tacke F
Evidence The rtA194T polymerase mutation impacts viral replication and susceptibility to tenofovir in hepatitis B e antigen-positive and hepatitis B e antigen-negative hepatitis B virus strains.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation