HBV Mutation Detail Information

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Mutation Information
Mutation Site L180M
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.V173L+rt.L180M+rt.M204V
Genotype/Subtype E
Viral Reference X75664.1
Literature Information
PubMed PMID 22195774
Clinical information Yes
Disease HBV-HIV coinfection
Published Year 2011
Journal BMC research notes
Title Emergence of HBV resistance to lamivudine (3TC) in HIV/HBV co-infected patients in The Gambia, West Africa.
Author Stewart B,Jobarteh ML,Sarge-Njie R,Alabi A,de Silva T,Peterson K,Peterson I,Whittle H,Rowland-Jones S,Jaye A,Cotten M,Mendy M
Evidence One patient showed the M204V+ L180M+ V174L+ triple mutation associated with a vaccine escape phenotype, which could be of public health concern in a country with a national HBV vaccination programme.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation