HBV Mutation Detail Information

> L80V Search Result

Mutation Information

Mutation Site	L80V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.M204I+rt.L80V
Genotype/Subtype	A;D
Country	Italy+other countries

Literature Information

PubMed PMID	19041149
Disease	HBV infection
Published Year	2009
Journal	Journal of hepatology
Title	The profile of mutational clusters associated with lamivudine resistance can be constrained by HBV genotypes.
Author	Svicher V,Gori C,Trignetti M,Visca M,Micheli V,Bernassola M,Salpini R,Gubertini G,Longo R,Niero F,Ceccherini-Silberstein F,De Sanctis GM,Spanò A,Cappiello G,Perno CF
Evidence	RtM204V clusters with mutations localized in the RT-B domain (rtV173L, rtL180M, and rtT184A/S) (bootstrap=0.94), while rtM204I clusters with mutations localized in the RT-A domain (rtS53N, rtT54Y, and rtL80I/V) (bootstrap=0.96) (without associations with HBsAg specific mutations).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation