Mutation Information
Mutation Site
|
V173L |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
D |
Relevant Drug
|
lamivudine (LAM) |
Country
|
Germany |
Literature Information
PubMed PMID
|
22892524
|
Disease
|
HBV infection
|
Published Year
|
2012 |
Journal
|
Antiviral therapy |
Title
|
Evolution of adefovir-resistant HBV polymerase gene variants after switching to tenofovir disoproxil fumarate monotherapy. |
Author
|
van Bömmel F,Trojan J,Deterding K,Wedemeyer H,Wasmuth HE,Hüppe D,Möller B,Bock FJ,Feucht HH,Berg T |
Evidence
|
Also, the mutations rtL80V, rtV173L, rtM180 and rtM204V were detect-able in some patients and the mutation rtI233V was detected in one patient (Figure 1A–1J).
|
|
|