HBV Mutation Detail Information

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Mutation Information
Mutation Site M204V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug lamivudine (LAM)
Country Korea
Literature Information
PubMed PMID 16618409
Disease Chronic hepatitis B
Published Year 2006
Journal Gastroenterology
Title Predominance of hepatitis B virus YMDD mutants is prognostic of viral DNA breakthrough.
Author Lee CH,Kim SO,Byun KS,Moon MS,Kim EO,Yeon JE,Yoo W,Hong SP
Evidence RFMP exploits differences in molecular masses between wild-type and variant bases of rtM204V/I following PCR amplification of HBV DNA with a lower limit of detection being 100 copies/mL.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation