HBV Mutation Detail Information

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Mutation Information

Mutation Site	M250F
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	D
Relevant Drug	lamivudine (LAM);entecavir (ETV)

Literature Information

PubMed PMID	20169198
Published Year	2010
Journal	PloS one
Title	Mechanistic characterization and molecular modeling of hepatitis B virus polymerase resistance to entecavir.
Author	Walsh AW,Langley DR,Colonno RJ,Tenney DJ
Evidence	Those that were large, replicated and could maintain the positioning of the primer:template, M250F/Y, retained ETV susceptibility.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation