HBV Mutation Detail Information

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Mutation Information
Mutation Site M204I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug lamivudine (LAM)
Literature Information
PubMed PMID 16856618
Disease Chronic hepatitis B
Published Year 2006
Journal Antiviral therapy
Title The clinical impact of early detection of the YMDD mutant on the outcomes of long-term lamivudine therapy in patients with chronic hepatitis B.
Author Paik YH,Han KH,Hong SP,Lee HW,Lee KS,Kim SO,Shin JE,Ahn SH,Chon CY,Moon YM
Evidence Cumulative viral breakthrough rates at 3 years was 75.0% and 14.3% in patients who had the rtM204I mutant and wild-type virus at 3 months, respectively (P=0.002).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation