HBV Mutation Detail Information

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Mutation Information

Mutation Site	T184L
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	A2
Viral Reference	X70185.1

Literature Information

PubMed PMID	22453135
Disease	Chronic hepatitis B
Published Year	2012
Journal	Antiviral research
Title	Long-term monitoring drug resistance by ultra-deep pyrosequencing in a chronic hepatitis B virus (HBV)-infected patient exposed to several unsuccessful therapy schemes.
Author	Sede M,Ojeda D,Cassino L,Westergaard G,Vazquez M,Benetti S,Fay F,Tanno H,Quarleri J
Evidence	Once the entecavir and tenofovir combined therapy was started, polymerase and consequently envelope gene mutations appeared at several positions at a higher frequency than before, including the entecavir resistance-associated mutation rtT184L.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation