|
Mutation Information
|
Mutation Site
|
T184S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.A200V+rt.T184S+rt.L80V;rt.A200V+rt.T184S+rt.L80I |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
18504191
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2008 |
|
Journal
|
Nan fang yi ke da xue xue bao = Journal of Southern Medical University |
|
Title
|
[Mutations of HBV polymerase gene sequence in lamivudine-resistant chronic hepatitis B patients]. |
|
Author
|
Wang C,Sun J,Chen JJ,Wang ZH,Hou JL |
|
Evidence
|
Other resistant substitutions included rtL80V/I, rtT184S, and rtA200V, and combined mutation of triple resistant substitutions was detected in HBV RT region of 5 patients by direct sequencing.
|
|
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HBV Mutation Detail Information