Mutation Information
Mutation Site
|
I169T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Country
|
China |
Literature Information
PubMed PMID
|
29119303
|
Disease
|
HBV infection
|
Published Year
|
2018 |
Journal
|
Virus genes |
Title
|
Evolution of drug-resistant mutations in HBV genomes in patients with treatment failure during the past seven years (2010-2016). |
Author
|
Zhang HY,Liu LG,Ye CY,Chen CH,Hang SX,Zhu Z,Shen HY,Huang ZY,Chen WY,Xue Y |
Evidence
|
Among the primary NA-resistance mutations, rtM204I (13.44%, 545/4055) occurred more frequently, followed by rtM204V (11.83%, 480/4055), rtN236T (5.97%, 242/4055), rtA181T (3.58%, 145/4055), and rtA181V (3.13%, 127/4055). Other mutations, such as rtI169T and rtM250V, were scarce (Fig. 1a).
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