HBV Mutation Detail Information

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Mutation Information
Mutation Site L180M
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.M204I+rt.T184L+rt.L180M
Relevant Drug lamivudine (LAM);adefovir (ADV)
Country China
Literature Information
PubMed PMID 19302908
Disease Chronic hepatitis B
Published Year 2009
Journal Clinical therapeutics
Title Evolution of hepatitis B virus polymerase mutations in a patient with HBeAg-positive chronic hepatitis B virus treated with sequential monotherapy and add-on nucleoside/nucleotide analogues.
Author Wang F,Wang H,Shen H,Meng C,Weng X,Zhang W
Evidence The rtM204I mutation was associated with compensatory mutations (rtL180M and rtT184L).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation