|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.N236T+rt.A181T |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
GQ872210
|
|
Relevant Drug
|
adefovir (ADV) |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
23197889
|
|
Disease
|
HBV infection
|
|
Published Year
|
2012 |
|
Journal
|
World journal of gastroenterology |
|
Title
|
Clonal evolution of hepatitis B virus polymerase gene mutations during lamivudine-adefovir combination treatment. |
|
Author
|
Ko SY,Kim BK,Kwon SY,Kim KH,Kim JH,Choe WH,Lee CH |
|
Evidence
|
ADV-resistant mutations, including rtA181V/T or rtN236T, were detected after 13 to 19 mo of LMV-ADV sequential monotherapy.
|
|
|
HBV Mutation Detail Information