HBV Mutation Detail Information

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Mutation Information

Mutation Site	T184S
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	C
Country	China

Literature Information

PubMed PMID	26889227
Disease	Chronic hepatitis B
Published Year	2016
Journal	Experimental and therapeutic medicine
Title	Evolution of entecavir-resistant hepatitis B virus during entecavir and adefovir dipivoxil combination therapy.
Author	Wang Y,Liu S,Chen YU,Zheng S,Zhou LI,Hua T,Sui S,Lu F,Duan Z
Evidence	Prior to the virological breakthrough, the ETV-associated variant, rtS202G, had been detected at month 24 and was present in ~20% of the viral population; v) after ADV therapy was initiated at month 37, the viral load gradually declined; the rtL180M, rtT184S, rtS202G and rtM204V variants were persistently dominant in the viral population during the combination therapy.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation