HBV Mutation Detail Information

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Mutation Information
Mutation Site I169V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.V173M+rt.I169V
Genotype/Subtype C
Relevant Drug entecavir (ETV)
Country Korea
Literature Information
PubMed PMID 28870025
Clinical information Yes
Disease Chronic hepatitis B
Published Year 2017
Journal Clinical and molecular hepatology
Title Clinical characteristics of patients with chronic hepatitis B who developed genotypic resistance to entecavir: Real-life experience.
Author Kim HJ,Cho YK,Jeon WK,Kim BI
Evidence The patterns of genotypic resistance to ETV were as follows: L180M + M204V + S202G (n=3); M204I + V173M (n=1); I169V + V173M (n=1); L180M + M204V + V173L (n=1); L180M + M204V + V173L + M250V (n=1); M204I + V214A + P237H (n=1).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation