|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
s.W196L+rt.M204I |
|
Genotype/Subtype
|
A;D |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
12853747
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2003 |
|
Journal
|
AIDS (London, England) |
|
Title
|
Prevalence and characterization of lamivudine-resistant hepatitis B virus mutations in HIV-HBV co-infected individuals. |
|
Author
|
Cooley L,Ayres A,Bartholomeusz A,Lewin S,Crowe S,Mijch A,Locarnini S,Sasadeusz J |
|
Evidence
|
A methionine to isoleucine substitution at codon 204 (rtM204I) of the reverse transcriptase of the HBV polymerase gene was present in four individuals.
|
|
|
HBV Mutation Detail Information