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Mutation Information
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Mutation Site
|
P512L |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
P |
Literature Information
|
PubMed PMID
|
9862871
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
1999 |
|
Journal
|
Hepatology (Baltimore, Md.) |
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Title
|
Transient selection of a hepatitis B virus polymerase gene mutant associated with a decreased replication capacity and famciclovir resistance. |
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Author
|
Pichoud C,Seignères B,Wang Z,Trépo C,Zoulim F |
|
Evidence
|
Other reports have described the occurrence of otherHBV polymerase mutations (P512L, T519S, I522L) in pa-tients with liver allograft who had been treated for chronicHBV infection with famciclovir for more than 6 months.
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HBV Mutation Detail Information