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HBV Mutation Detail Information

> V378I Search Result


Mutation Information
Mutation Site V378I
Mutation Type Amino acid level
Gene/Protein/Region Type P
Relevant Drug famciclovir (FCV)
Literature Information
PubMed PMID 10365797
Disease Chronic hepatitis B
Published Year 1999
Journal Journal of hepatology
Title Absence of mutations in the YMDD motif/B region of the hepatitis B virus polymerase in famciclovir therapy failure.
Author Günther S,von Breunig F,Santantonio T,Jung MC,Gaeta GB,Fischer L,Sterneck M,Will H
Evidence In patients with a breakthrough, 378-V-->I and 424-N-->D mutations emerged in the N terminal part of the polymerase domain during follow-up.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation