|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.V173L+rt.M204V+rt.L180M |
|
Genotype/Subtype
|
B;C |
|
Viral Reference
|
M54923.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
22001270
|
|
Disease
|
HBV infection
|
|
Published Year
|
2012 |
|
Journal
|
The Journal of antimicrobial chemotherapy |
|
Title
|
Identification of hepatitis B virus rtS117F substitution as a compensatory mutation for rtM204I during lamivudine therapy. |
|
Author
|
Lin CL,Chien RN,Hu CC,Lai MW,Yeh CT |
|
Evidence
|
Coexisting mutation rtV173L 0 (0) 0 (0) 2 (5) 1.000 0.606 0.641 rtL180M 3 (60) 0 (0) 16 (40) 0.071 0.389 0.122 rtL801 2 (40) 1 (25) 6 (15) 0.571 0.185 0.629.
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|
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HBV Mutation Detail Information