Mutation Information
Mutation Site
|
A181V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Combined Mutation
|
rt.N236T+rt.A181V;rt.A181V+rt.I233V |
Relevant Drug
|
adefovir (ADV) |
Country
|
China |
Literature Information
PubMed PMID
|
26079809
|
Disease
|
HBV infection
|
Published Year
|
2016 |
Journal
|
Antiviral therapy |
Title
|
Increased occurrence of mutant rtI233V of HBV in patients receiving adefovir therapy. |
Author
|
Liu Y,Xin S,Ye X,Chen R,Xu Z,Li X,Ye H,Cheng S,Xu D |
Evidence
|
Eight patients with rtI233V +/- rtA181V/rtN236T had virological breakthrough in the clinical course of ADV treatment.
|
|
|