Mutation Information
Mutation Site
|
I233V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
adefovir (ADV) |
Country
|
Turkey |
Literature Information
PubMed PMID
|
20382061
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2010 |
Journal
|
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases |
Title
|
Monitoring of hepatitis B virus surface antigen escape mutations and concomitantly nucleos(t)ide analog resistance mutations in Turkish patients with chronic hepatitis B. |
Author
|
Sayan M,Sentürk O,Akhan SÇ,Hülagü S,Cekmen MB |
Evidence
|
Interestingly, the treatment-naive patients had preexisting drug resistance mutations related to lamivudine (rtL180M+rtM204I), adefovir (rtA181V, rtQ215S, rtI233V), entecavir (intermediate susceptibility with rtL180M+rtM204IHBV variant), telbivudine (rtL180M+rtM204I), and tenofovir (rtA194T).
|
|
|