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Mutation Information
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Mutation Site
|
L527P |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
P |
Literature Information
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PubMed PMID
|
10827158
|
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Disease
|
HBV infection
|
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Published Year
|
2000 |
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Journal
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Hepatology (Baltimore, Md.) |
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Title
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Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistant mutants during prolonged lamivudine therapy. |
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Author
|
Yeh CT,Chien RN,Chu CM,Liaw YF |
|
Evidence
|
Other mutants harboring mutations in domain B and C ofHBV polymerase sequence were as followed: L528M/A529T,L528M/Y551N, L528M/M552E, L528M/D553V, L528M/L527P, L528R/A529T, Q530-to-Stop, M552Q, and L527P.
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HBV Mutation Detail Information