HBV Mutation Detail Information

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Mutation Information

Mutation Site	P509H
Mutation Type	Amino acid level
Gene/Protein/Region Type	P
Country	Argentine

Literature Information

PubMed PMID	16757620
Disease	Chronic hepatitis B
Published Year	2006
Journal	Journal of clinical microbiology
Title	Unusual naturally occurring humoral and cellular mutated epitopes of hepatitis B virus in a chronically infected argentine patient with anti-HBs antibodies.
Author	Cuestas ML,Mathet VL,Ruiz V,Minassian ML,Rivero C,Sala A,Corach D,Alessio A,Pozzati M,Frider B,Oubiña JR
Evidence	The two clones mentioned above exhibiting amino acid substitutions in the MHC-II-restricted 136 to 155 S epitope (I152F and P153T) also showed the corresponding substitutions (H508L and P509H) in both the MHC-II 503 to 517 Pol epitope (26) and the nested MHC-I 504 to 512 Pol epitope (Fig. (Fig.3)3) (26).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation