HBV Mutation Detail Information

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Mutation Information

Mutation Site	L180M
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	lamivudine (LAM)

Literature Information

PubMed PMID	19107976
Disease	Chronic hepatitis B
Published Year	2009
Journal	Journal of medical virology
Title	Lamivudine monoprophylaxis and adefovir salvage for liver transplantation in chronic hepatitis B: a seven-year follow-up study.
Author	Limquiaco JL,Wong J,Wong VW,Wong GL,Tse CH,Chan HY,Kwan KY,Lai PB,Chan HL
Evidence	Among the early deaths, one patient has pre-existinglamivudine resistance (rtL180M and rtM204V) after43 weeks of lamivudine pre-transplant and he died ofliver failure 15 weeks post-transplant.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation