Mutation Information
Mutation Site
|
H94N |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Literature Information
PubMed PMID
|
17692425
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2007 |
Journal
|
Journal of hepatology |
Title
|
Pooled analysis of amino acid changes in the HBV polymerase in patients from four major adefovir dipivoxil clinical trials. |
Author
|
Borroto-Esoda K,Miller MD,Arterburn S |
Evidence
|
Two patients with the rtA181V and/or rtN236T mutations also developed other conserved site mutations; one patient in study GS-98-438 who developed rtN236T also developed rtH94N and one patient in study GS-98-437 who developed rtA181V also developed rtN36D.
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