HBV Mutation Detail Information

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Mutation Information
Mutation Site M204V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.M204V+rt.L180M
Genotype/Subtype A
Relevant Drug lamivudine (LAM)
Country Brazil
Literature Information
PubMed PMID 18036224
Disease Chronic hepatitis B
Published Year 2007
Journal BMC microbiology
Title Hepatitis B virus genotypes circulating in Brazil: molecular characterization of genotype F isolates.
Author Mello FC,Souto FJ,Nabuco LC,Villela-Nogueira CA,Coelho HS,Franz HC,Saraiva JC,Virgolino HA,Motta-Castro AR,Melo MM,Martins RM,Gomes SA
Evidence One (209-CW) displayed the double rtL180M-rtM204V lamivudine-resistance mutation and the other (043-N) showed an additional rtV173L mutation, which is also associated with lamivudine resistance (Table 3).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation