HBV Mutation Detail Information

> A181V Search Result


Mutation Information
Mutation Site A181V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.N236T+rt.A181V
Relevant Drug adefovir (ADV)
Literature Information
PubMed PMID 16729316
Disease Chronic hepatitis B
Published Year 2006
Journal Hepatology (Baltimore, Md.)
Title Increased risk of adefovir resistance in patients with lamivudine-resistant chronic hepatitis B after 48 weeks of adefovir dipivoxil monotherapy.
Author Lee YS,Suh DJ,Lim YS,Jung SW,Kim KM,Lee HC,Chung YH,Lee YS,Yoo W,Kim SO
Evidence We compared the emergence of the ADV-resistant mutations rtA181V/T and rtN236T between LAM-resistant patients and treatment-naive patients at 48 weeks of ADV monotherapy.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation