HBV Mutation Detail Information

> A181T Search Result

Mutation Information

Mutation Site	A181T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	lamivudine (LAM);adefovir (ADV)

Literature Information

PubMed PMID	20875460
Published Year	2010
Journal	Antiviral research
Title	Hepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery.
Author	Rhee SY,Margeridon-Thermet S,Nguyen MH,Liu TF,Kagan RM,Beggel B,Verheyen J,Kaiser R,Shafer RW
Evidence	Among the 10 well-characterized N(t)RTI-resistance mutations, L80I/V, V173L, L180M, A181T, T184S, S202G and M204I/V were significantly associated with treatment with lamivudine, an L-nucleoside analog

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation