Mutation Information
Mutation Site
|
M552I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
P |
Viral Reference
|
AY040627
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
PubMed PMID
|
17317127
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2008 |
Journal
|
Microbiological research |
Title
|
Dynamic changes of hepatitis B virus polymerase gene including YMDD motif in lamivudine-treated patients with chronic hepatitis B. |
Author
|
Feng B,Wei L,Chen M,Wang L |
Evidence
|
Among five patients after 12 months of lamivudine treatment, M552I mutations in two patients with HBV DNA rebounding and D553G mutation in one non-responder were detected except two patients with negative HBV DNA consecutively.
|
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