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Mutation Information
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Mutation Site
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M250I |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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RT |
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Country
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China |
Literature Information
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PubMed PMID
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32569703
|
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Disease
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Chronic hepatitis B
|
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Published Year
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2020 |
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Journal
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Antiviral research |
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Title
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Hepatitis B virus mutation pattern rtA181S+T184I+M204I may contribute to multidrug resistance in clinical practice: Analysis of a large cohort of Chinese patients. |
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Author
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Chen R,Liu Y,Luo D,Si L,Huang B,Wang J,Li X,Cheng F,Xu D,Duan C |
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Evidence
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The other two mutants rtA181S + T184I + M204I + M250I (5% in sample B5) and rtA181S + T184I + M204I + M250V (5% in sample B8) were detected for the duration but not detected in samples B6 and B7. Afterwards, therapy was switched to TDF and HBV DNA declined to undetectable level within 4 months (Fig. 1B).
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HBV Mutation Detail Information