HBV Mutation Detail Information

> T184G Search Result


Mutation Information
Mutation Site T184G
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Viral Reference X75665.1
Relevant Drug entecavir (ETV)
Country Japan;United States; Hong Kong
Literature Information
PubMed PMID 19933798
Disease Chronic hepatitis B
Published Year 2010
Journal Antimicrobial agents and chemotherapy
Title Mechanism of entecavir resistance of hepatitis B virus with viral breakthrough as determined by long-term clinical assessment and molecular docking simulation.
Author Mukaide M,Tanaka Y,Shin-I T,Yuen MF,Kurbanov F,Yokosuka O,Sata M,Karino Y,Yamada G,Sakaguchi K,Orito E,Inoue M,Baqai S,Lai CL,Mizokami M
Evidence In the 29 patients treated with ETV for 3 years, T184SCGA, T184ILMF, S202G, and S202C were found in 5 (17.2%), 4 (13.8%), 9 (31.0%), and 1 (3.4%), respectively.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation