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Mutation Information
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Mutation Site
|
M204I |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
Literature Information
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PubMed PMID
|
21742757
|
|
Clinical information
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Yes
|
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Disease
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Chronic hepatitis B
|
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Published Year
|
2011 |
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Journal
|
Nucleic acids research |
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Title
|
Ultra-deep pyrosequencing analysis of the hepatitis B virus preCore region and main catalytic motif of the viral polymerase in the same viral genome. |
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Author
|
Homs M,Buti M,Quer J,Jardí R,Schaper M,Tabernero D,Ortega I,Sanchez A,Esteban R,Rodriguez-Frias F |
|
Evidence
|
As was seen in the baseline samples, the wild-type form of Position 204 was highly predominant (>99%), but in the four samples, a low percentage of the main rtM204V/I mutant forms (0.07–0.2%) and a significant percentage of other variants (0.09–0.12%) were detected.
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HBV Mutation Detail Information