|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.L180M;rt.M204V+rt.L180M+rt.V173L |
|
Genotype/Subtype
|
A;C;F;G |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Brazil |
Literature Information
|
PubMed PMID
|
18211717
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2008 |
|
Journal
|
BMC microbiology |
|
Title
|
Hepatitis B virus genotypes and resistance mutations in patients under long term lamivudine therapy: characterization of genotype G in Brazil. |
|
Author
|
Bottecchia M,Souto FJ,O KM,Amendola M,Brandão CE,Niel C,Gomes SA |
|
Evidence
|
Fifteen patients showed the L180M/M204V lamivudine resistant double mutation.
|
|
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HBV Mutation Detail Information