HBV Mutation Detail Information

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Mutation Information

Mutation Site	M204S
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.M204I+rt.L80I
Relevant Drug	lamivudine (LAM);entecavir (ETV);tenofovir (TDF);telbivudine (LDT)

Literature Information

PubMed PMID	16673294
Published Year	2006
Journal	Seminars in liver disease
Title	Antiviral drug resistance: clinical consequences and molecular aspects.
Author	Bartholomeusz A,Locarnini SA
Evidence	Nine major patterns of mutations asso-ciated with LMV resistance have so far been reported:(1) rtM204I/V+tL180M, (2) rtM204I, (3) rtV173L+tL180M+tM204V, (4) rtL80I+tM204I, (5)rtQ215S+tM204I/VrtL180M, (6) rtI169T+tV173L+tL180M+tM204V, (7) rtA181T, (8)rtT184S+tM204I/VrtL180M, and (9) rtM204S+tL180M.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation