HBV Mutation Detail Information

> M552I Search Result

Mutation Information

Mutation Site	M552I
Mutation Type	Amino acid level
Gene/Protein/Region Type	P
Relevant Drug	lamivudine (LAM);famciclovir (FCV)

Literature Information

PubMed PMID	10655370
Disease	Chronic hepatitis B
Published Year	2000
Journal	Journal of clinical microbiology
Title	Line probe assay for monitoring drug resistance in hepatitis B virus-infected patients during antiviral therapy.
Author	Stuyver L,Van Geyt C,De Gendt S,Van Reybroeck G,Zoulim F,Leroux-Roels G,Rossau R
Evidence	Previously genotyped HBV strains isolated from treated and untreated patients were amplified with primers specific for the HBV polymerase region from amino acids 465 to 562. A set of 38 highly specific oligonucleotide probes covering three different codon positions, L528M, M552V/I, and V/L/M555I, were selected.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation