|
Mutation Information
|
Mutation Site
|
T184A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.T184A+rt.L180M;rt.T184A+rt.N238T+rt.H238T+rt.S213T+rt.M204V+rt.L180M |
|
Relevant Drug
|
entecavir (ETV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
26309637
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2015 |
|
Journal
|
International journal of clinical and experimental medicine |
|
Title
|
Detection and analysis of resistance mutations of hepatitis B virus. |
|
Author
|
He X,Wang F,Huang B,Chen P,Zhong L |
|
Evidence
|
Single base mutations included L180M, M204I, M204V, V207M, S213T, N/H238T, T184A, V214A, N236A, V173L, L180M/I, A181T, N236T and N/H238T/A. Of these mutations, M204I had the highest detection rate, followed by L180M, M204V and V173L (Figure 1).
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HBV Mutation Detail Information