|
Mutation Information
|
Mutation Site
|
T184L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.T184L+rt.L180M |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
28300730
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2017 |
|
Journal
|
Antiviral therapy |
|
Title
|
The enrichment of HBV immune-escape mutations during nucleoside/nucleotide analogue therapy. |
|
Author
|
Shan M,Shen Z,Sun H,Zheng J,Zhang M |
|
Evidence
|
The double (rtV173L+rtM204I) and triple (rtV173L/T184L+rtL180M+rtM204V) mutations not only conferred resistance to LMV, but also resulted in two mutations in S protein.
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|
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HBV Mutation Detail Information