HBV Mutation Detail Information

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Mutation Information
Mutation Site V214A
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.K266V+rt.R266V+rt.I266V+rt.Y257H+rt.Q215H+rt.V214A+rt.V207I+rt.I187L+rt.V173L+rt.L164M+rt.F122L;rt.Y257W+rt.N238A+rt.P237T+rt.Q215S+rt.V214A+rt.M204V+rt.L180M+rt.R153W
Genotype/Subtype D
Relevant Drug lamivudine (LAM)
Country Rome
Literature Information
PubMed PMID 19442845
Disease Chronic hepatitis B
Published Year 2009
Journal Journal of virological methods
Title A sensitive direct sequencing assay based on nested PCR for the detection of HBV polymerase and surface glycoprotein mutations.
Author Vincenti D,Solmone M,Garbuglia AR,Iacomi F,Capobianchi MR
Evidence Direct sequencing was able to show pol mutations not revealed by DR v2, such as rtV214A, rtQ215H/S, and rtM250V.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation