HBV Mutation Detail Information

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Mutation Information

Mutation Site	M204I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	A
Country	Spain

Literature Information

PubMed PMID	22666402
Disease	Chronic hepatitis B
Published Year	2012
Journal	PloS one
Title	Ultra-deep pyrosequencing detects conserved genomic sites and quantifies linkage of drug-resistant amino acid changes in the hepatitis B virus genome.
Author	Rodriguez-Frías F,Tabernero D,Quer J,Esteban JI,Ortega I,Domingo E,Cubero M,Camós S,Ferrer-Costa C,Sánchez A,Jardí R,Schaper M,Homs M,Garcia-Cehic D,Guardia J,Esteban R,Buti M
Evidence	The 10 most variable RT substitutions observed during sequential NA treatment, blindly selected after SD sorting and all associated with NA resistance (rtL180M, rtM204V, rtS202G, rtV207I, rtA181T, rtL173V, rtI169T, rtV191I, rtM204I, and rtT184A) (Table 3), were included in the linkage analysis.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation