HBV Mutation Detail Information

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Mutation Information

Mutation Site	I169T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Viral Reference	AB713528
Relevant Drug	entecavir (ETV)
Country	Indonesian

Literature Information

PubMed PMID	27492206
Disease	HBV infection
Published Year	2016
Journal	The Kobe journal of medical sciences
Title	Different Variants in Reverse Transcriptase Domain Determined by Ultra-deep Sequencing in Treatment-naïve and Treated Indonesian Patients Infected with Hepatitis B Virus.
Author	Wasityastuti W,Yano Y,Widasari DI,Yamani LN,Ratnasari N,Heriyanto DS,Okada R,Tanahashi T,Murakami Y,Azuma T,Hayashi Y
Evidence	Primary and secondary NA resistance at nine hotspots (rtI169T, rtV173L, rtL180M/I, rtA181T/V, rtT184A/S, rtS202G/I, rtM204V, rtN236T and rtM250V) was investigated using ultra-deep sequencing in treatment naïve and treated Indonesian patients infected with HBV.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation