HBV Mutation Detail Information

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Mutation Information

Mutation Site	R153Q
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	C
Country	China

Literature Information

PubMed PMID	27650283
Disease	HBV infection
Published Year	2017
Journal	Journal of hepatology
Title	Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA.
Author	Xiang KH,Michailidis E,Ding H,Peng YQ,Su MZ,Li Y,Liu XE,Dao Thi VL,Wu XF,Schneider WM,Rice CM,Zhuang H,Li T
Evidence	Due to the overlapping nature of the S and RT gene regions, mutations in the S gene may result in concomitant mutations in RT, such as sC69*/rtS78T, sL98V/rtS106C and sG145R/rtR153Q, potentially affecting RT activity and HBV replication.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation